Advancing Neuroscience Research by Studying Mice

Professor Davison’s lab at BU is interested in the neural circuits underlying olfaction in mice. The overarching goal is to establish the exact circuitry and neural computations that map chemical cues onto stereotyped and learned behaviors. ​

​During my time in the lab, I was collecting behavioral data with a thermistor-implanted mouse. This device is surgically inserted into the mouse nasal cavity and allows us to record changes in temperature and sniff rate when the mouse is exposed to sucrose pellets with various odors. I prepared both the pellets and was responsible for managing the mouse for various behavioral assays. This included inducing anesthesia and managing attachment to data collection devices. Following data collection, I trained a neural network and applied it in the analysis of postural changes of the mouse. ​​

Looking back at this internship, I particularly enjoyed the computational aspect of training, evaluating, and refining the neural network. Paired with the behavioral data I collected, this was the perfect combination of animal interaction and analysis using advanced tools. I built on my python skills I gained earlier this summer and was simultaneously able to advance my skills in handling live mice. I think this internship has made it clear to me that beyond an MD, I might want to pursue an MD-PhD. Neuroscience research is something I am passionate about and want to pursue in the future. 

Internship funded by the Dr. Cheryl M. Coffin '75 Internship Fund.