Upcoming Seminars

September 9, 2022

Sulfur-Fluoride Exchange (SuFEx) Chemistry as a Tool Toward Drug Discovery with Nicholas D. Ball, Associate Professor of Chemistry at Pomona College

Research Abstract: Sulfur-based molecules have long found success in drug discovery. In particular, S(VI) compounds have found outstanding success as antimicrobial, anticonvulsants, and other uses. S(VI) fluorides have emerged as a class of compounds that show promise in enabling the generation of large libraries of stable synthons toward adding sulfur into target molecules. Sulfur-fluoride exchange (SuFEx) has emerged a key synthetic strategy employed to unlock the reactivity of sulfur fluorides. Read the full abstract here.

September 16, 2022

The Search for New Microbial Natural Products and Biocatalysts with Lesley-Ann Giddings, Assistant Professor of Chemistry at Smith College

Research Abstract: In the search for new microbial secondary metabolites, chemists have traditionally explored accessible terrestrial environments. However, since the 1990s, all of the “low hanging fruit” has been picked and natural product rediscovery rates increased. As a result, underexplored environments, such as extreme ecosystems, are now being investigated for these metabolites and their biosynthetic enzymes. Read the full abstract here.