Jack Bateman

Samuel S. Butcher Associate Professor in the Natural Sciences

Teaching this semester

BIOL 2112. Genetics and Molecular Biology

Jack Bateman
Integrated coverage of organismic and molecular levels of genetic systems. Topics include modes of inheritance, the structure and function of chromosomes, the mechanisms and control of gene expression, recombination, mutagenesis, techniques of molecular biology, and human genetic variation. Laboratory sessions are scheduled.

My lab studies how chromosomes are organized within the three-dimensional space of the nucleus, and, in particular, how physical interactions between chromosomes can influence gene expression. We focus on Drosophila melanogaster in part because of the amazing genetic tools available, and in part because there is extensive pairing between homologous chromosomes in this system, providing us with a simple model to study interchromosomal interactions. Some of our projects branch out into the development of new genetic technologies and resources for the Drosophila research community.

Education

  • Postdoctoral Fellow, Department of Genetics, Harvard Medical School
  • Ph.D. in Cellular and Developmental Biology, Department of Cell Biology, Harvard Medical School
  • B.Sc. in Biology, Dalhousie University

Recent Publications (* denotes undergraduate author)

Blick, A.J.*1, Mayer-Hirshfeld, I.* 1, Malibiran, B.R.*, Cooper, M.A.*, Martino, P.A.*, Johnson, J.E., and Bateman, J.R.. 2016. The Capacity to Act in Trans Varies Among Drosophila Enhancers. Genetics 203: 203-218. (1Equal contribution)

Bing, X., Rzezniczak, T.Z., Bateman, J.R., and Merritt, T.J.S. 2014. Transvection-based gene regulation in Drosophila is a complex and plastic trait. G3: Genes, Genomes, Genetics 4: 2175-2187.

Bateman, J.R., Palopoli, M.F., Dale, S.T.*, Stauffer, J.E.*, Shah, A.L.*, Johnson, J.E., Walsh, C.W.*, Flaten, H.*, Parsons, C.M.* 2013. Captured segment exchange: A strategy for custom engineering large genomic regions in Drosophila melanogaster. Genetics 193: 421-430. 

Bateman, J.R., Johnson, J.E., Locke, M.N.* 2012. Comparing enhancer action in cis and in trans. Genetics 191: 1143-1155. 

Bateman, J.R.,1 Larschan, E.,1 D’Souza, R., Marshall, L.S.*, Dempsey, K.E.*, Johnson, J.E., Mellone, B.G., and Kuroda, M.I. 2012. A genome-wide screen identifies genes that affect somatic homolog pairing in Drosophila. G3: Genes, Genomes, Genetics. 2: 731-740. (1equal contribution)

Sun, F.F.*, Johnson, J.E., Zeidler, M.P., and Bateman, J.R. 2012. Simplified insertion of transgenes onto balancer chromosomes via recombinase-mediated cassette exhange. G3: Genes, Genomes, Genetics. 2: 551-553.