An examination of current concepts of embryonic development, with an emphasis on experimental design. Topics include cell fate specification, morphogenetic movements, cell signaling, differential gene expression and regulation, organogenesis, and the evolutionary context of model systems. Project-oriented laboratory work emphasizes experimental methods. Lectures and three hours of laboratory per week. Textbook is Princlples of Development 4e by Wolpert & Tickle.
Syllabus - Lectures - Lab - Assignments/Exams - Readings
"How the first embryon-fibre, sphere, or cube,
Lives in new forms,-a line,-a ring,-a tube;
Closed in the womb with limbs unfinish'd laves,
Sips with rude mouth the salutary waves;
Seeks round its cell the sanguine streams, that pass,
And drinks with crimson gills the vital gas;
Weaves with soft threads the blue meandering vein,
The heart's red concave, and the silver brain;
Leads the long nerve, expands the impatient sense,
And clothes in silken skin the nascent Ens."
- Dewhurst Bilsborrow in Erasmus Darwin's Zoonomia (1794)