Associate Professor of Biology
Teaching this semester
BIOL 1109. Scientific Reasoning in Biology
Pamela Bryer William Jackman
Lectures examine fundamental biological principles, from the sub-cellular to the ecosystem level with an emphasis on critical thinking and the scientific method. Laboratory sessions will help develop a deeper understanding of the techniques and methods used in the biological science by requiring students to design and conduct their own experiments. Lecture and weekly laboratory/discussion groups. To ensure proper placement, students must take the biology placement examination and must be recommended for placement in Biology 1109.
BIOL 3307. Evolutionary Developmental Biology
Advanced seminar investigating the synergistic but complex interface between the fields of developmental and evolutionary biology. Topics include the evolution of novel structures, developmental constraints to evolution, evolution of developmental gene regulation, and the generation of variation. Readings and discussions from the primary scientific literature.
My research investigates the genetic control of vertebrate embryonic tooth development. In particular we study how cell-cell signaling controls cellular behaviours such as proliferation, migration, and apoptosis, during tooth organogenesis. We use zebrafish and a variety of other fish species as models in this research because we are also interested in how developmental mechanisms have changed during evolution.
Jeffrey C. Yu*, Zachary D. Fox*, James L. Crimp*, Hana E. Littleford*, Andrea L. Jowdry, and William R. Jackman. (2015). Hedgehog signaling regulates dental papilla formation and tooth size during zebrafish odontogenesis. Developmental Dynamics 244, 577-590. doi:10.1002/DVDY.24258
William R. Jackman, Shelby H. Davies*, David B. Lyons*, Caitlin K. Stauder*, Benjamin R. Denton-Schneider*, Andrea Jowdry, Sharon R. Aigler, Scott A. Vogel*, and David W. Stock. (2013) Manipulation of Fgf and Bmp signaling in teleost fishes suggests potential pathways for the evolutionary origin of multicuspid teeth. Evolution and Development 15:2, 107-118. doi:10.1111/ede.12021
Pawat Seritrakul*, Eric Samarut, Tenzing TS Lama*, Yann Gibert, Vincent Laudet, and William R Jackman. (2012) Retinoic acid expands the evolutionarily reduced dentition of zebrafish. The FASEB Journal 26, 5014-5024. doi:10.1096/fj.12-209304
William R. Jackman, James J. Yoo*, and David W. Stock. (2010). Hedgehog signaling is required at multiple stages of zebrafish tooth development. BMC Developmental Biology 10:119, doi:10.1186/1471-213X-10-119
Yann Gibert, Laure Bernard, Melanie Debiais-Thibaud, Franck Bourrat, Jean-Stephane Joly, Karen Pottin, Axel Meyer, Sylvie Retaux, David W. Stock, William R. Jackman, Pawat Seritrakul*, Gerrit Begemann and Vincent Laudet. (2010). Formation of oral and pharyngeal dentition in teleosts depends on differential recruitment of retinoic acid signaling. The FASEB Journal 24, 3298-3309, doi:10.1096/fj.09-147488
Yoshiyuki Yamamoto, Mardi S. Byerly, William R. Jackman, and William R. Jeffery. (2009). Pleiotropic functions of embryonic sonic hedgehog expression link jaw and taste bud amplification with eye loss during cavefish evolution. Developmental Biology 330, 200-211, doi:10.1016/j.ydbio.2009.03.003
William R. Jackman and David W. Stock. (2006). Transgenic analysis of Dlx regulation in fish tooth development reveals evolutionary retention of enhancer function despite organ loss. Proceedings of the National Academy of Sciences of the USA 103, 19390-19395.
David W. Stock, William R. Jackman, and Josh Trapani. (2006). Developmental genetic mechanisms of evolutionary tooth loss in cypriniform fishes. Development 133, 3127-3137.
William R. Jackman, Bruce W. Draper, and David W. Stock. (2004). FGF signaling is required for zebrafish tooth development. Developmental Biology 274, 139-157.
William R. Jackman, Jolee M. Mougey*, Georgia D. Panopoulou, and Charles B. Kimmel. (2004). crabp and maf highlight the novelty of the amphioxus club-shaped gland. Acta Zoologica (Stockholm) 85, 91-99.
William R. Jackman and Charles B. Kimmel. (2002). Coincident iterated gene expression in the amphioxus neural tube. Evolution and Development 4, 366-374.
Lisa Maves, William R. Jackman, and Charles B. Kimmel. (2002). FGF3 and FGF8 mediate a rhombomere 4 signaling activity in the zebrafish hindbrain. Development 129, 3825-3837.
William R. Jackman, James A. Langeland, and Charles B. Kimmel. (2000). islet reveals segmentation in the amphioxus hindbrain homolog. Developmental Biology 220, 16-26.
James A. Langeland, Jill M. Tomsa*, William R. Jackman Jr., and Charles B. Kimmel. (1998). An amphioxus snail gene: Expression in paraxial mesoderm and neural plate suggests a conserved role in patterning the chordate embryo. Development Genes and Evolution 208, 569–577.
Timothy Quinn and William R. Jackman*. (1994). Influence of diet on detection of fecal bile acids by thin-later chromatography. Journal of Wildlife Management. 58:295-299.
- B.S., University of Washington
- Ph.D., University of Oregon
- Postdoc, University of Colorado Boulder