Infrared spectroscopy is a type of spectroscopy that uses the infrared portion of the electromagnetic spectrum. Infrared spectroscopy works because chemical bonds have specific frequencies at which they vibrate. These resonant frequencies are dependent on the length of the bond, and the mass of the atoms connected by the bond. Therefore, the frequency of the vibrations can be associated with a particular bond type. Bonds can vibrate in six different ways, symmetrical and asymmetrical stretching, scissoring, rocking, wagging and twisting.
Paras Trivedi, Researcher
Multiscale Analysis of Ciprofloxacin Reactions with Solid and Aqueous Ferric Species
Abstract: Accurate risk assessment and effective management of aquatic and soil environments contaminated with human and veterinary antibiotics, such as ciprofloxacin, require systematic compilation of mechanistic and quantitative information on antibiotic speciation chemistry in the presence of ubiquitous sorbents, such as iron oxides. Combined results of ATR-FTIR and UV-VIS spectroscopic studies, and computational molecular modeling suggest that ciprofloxacin mainly interacts electrostatically with ferric species via its carboxylate group. However, the extent of participation of these functional groups and thus the ultimate nature of the sorption reaction is predominantly a function of the physicochemical properties of the ferric species (surface charge density and degree of crystallinity). Complementary XAS studies, at Fe K-edge, reveal that the local structures of the ciprofloxacin-reacted ferric species are akin to those of unreacted ferric species, and thus corroborate the electrostatic interaction between them and cipro.