Spring 2010 Courses

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058. Drug Discovery
Danielle Dube M  1:30 - 2:25
W  1:30 - 2:25
F  1:30 - 2:25
Druckenmiller-024
The process of drug discovery of medicinal compounds has evolved over millennia, from the shaman’s use of medicinal herbs to the highly evolved techniques of rational design and high-throughput screening used by today’s pharmaceutical industry. Examines past and present approaches to drug discovery, with an emphasis on the natural world as a source of drugs, historical examples of drug discovery, and the experiments undertaken to validate a drug. Encourages students to take initial steps to identify novel therapeutics and to directly compare conventional versus herbal remedies in integrated laboratory exercises. Assumes no background in science. Not open to students who have credit for a chemistry course numbered 100 or higher.
105. Perspectives in Environmental Science
John Lichter T  10:00 - 11:25
TH 10:00 - 11:25
Druckenmiller-004
Functioning of the earth system is defined by the complex and fascinating interaction of processes within and between four principal spheres: land, air, water, and life. Leverages key principles of environmental chemistry and ecology to unravel the intricate connectedness of natural phenomena and ecosystem function. Fundamental biological and chemical concepts are used to understand the science behind the environmental dilemmas facing societies as a consequence of human activities. Laboratory sessions consist of local field trips, laboratory experiments, group research, case study exercises, and discussions of current and classic scientific literature.
109. General Chemistry
Ronald Christensen M  10:30 - 11:25
W  10:30 - 11:25
F  10:30 - 11:25
Druckenmiller-016
Introduction to models of atomic structure, chemical bonding, and intermolecular forces; characterization of chemical systems at equilibrium and spontaneous processes; the rates of chemical reactions; and special topics. Lectures, review sessions, and four hours of laboratory work per week. To ensure proper placement, students must take the chemistry placement examination prior to registering for Chemistry 109.
109. General Chemistry
Elizabeth Stemmler M  11:30 - 12:25
W  11:30 - 12:25
F  11:30 - 12:25
Druckenmiller-016
Introduction to models of atomic structure, chemical bonding, and intermolecular forces; characterization of chemical systems at equilibrium and spontaneous processes; the rates of chemical reactions; and special topics. Lectures, review sessions, and four hours of laboratory work per week. To ensure proper placement, students must take the chemistry placement examination prior to registering for Chemistry 109.
109. General Chemistry
Laura Voss T  10:00 - 11:25
TH 10:00 - 11:25
Druckenmiller-016
Introduction to models of atomic structure, chemical bonding, and intermolecular forces; characterization of chemical systems at equilibrium and spontaneous processes; the rates of chemical reactions; and special topics. Lectures, review sessions, and four hours of laboratory work per week. To ensure proper placement, students must take the chemistry placement examination prior to registering for Chemistry 109.
226. Organic Chemistry II
Michael Danahy M  8:30 - 9:25
W  8:30 - 9:25
F  8:30 - 9:25
Druckenmiller-016
Continuation of the study of the compounds of carbon. Highlights the reactions of aromatic, carbonyl-containing, and amine functional groups. Mechanistic reasoning provides a basis for understanding these reactions. Skills for designing logical synthetic approaches to complex organic molecules are developed. Chemistry 225 and 226 cover the material of the usual course in organic chemistry and form a foundation for further work in organic chemistry and biochemistry. Lectures, conference, and four hours of laboratory work per week.
226. Organic Chemistry II
Richard Broene M  9:30 - 10:25
W  9:30 - 10:25
F  9:30 - 10:25
Druckenmiller-020
Continuation of the study of the compounds of carbon. Highlights the reactions of aromatic, carbonyl-containing, and amine functional groups. Mechanistic reasoning provides a basis for understanding these reactions. Skills for designing logical synthetic approaches to complex organic molecules are developed. Chemistry 225 and 226 cover the material of the usual course in organic chemistry and form a foundation for further work in organic chemistry and biochemistry. Lectures, conference, and four hours of laboratory work per week.
226. Organic Chemistry II
Jennifer Krumper M  9:30 - 10:25
W  9:30 - 10:25
F  9:30 - 10:25
Druckenmiller-016
Continuation of the study of the compounds of carbon. Highlights the reactions of aromatic, carbonyl-containing, and amine functional groups. Mechanistic reasoning provides a basis for understanding these reactions. Skills for designing logical synthetic approaches to complex organic molecules are developed. Chemistry 225 and 226 cover the material of the usual course in organic chemistry and form a foundation for further work in organic chemistry and biochemistry. Lectures, conference, and four hours of laboratory work per week.
231. Biochemistry and Cell Biology
Bruce Kohorn T  8:30 - 9:55
TH 8:30 - 9:55
Druckenmiller-020
Focuses on the structure and function of cells as we have come to know them through the interpretation of direct observations and experimental results. Emphasis is on the scientific (thought) processes that have allowed us to understand what we know today, emphasizing the use of genetic, biochemical, and optical analysis to understand fundamental biological processes. Covers details of the organization and expression of genetic information, and the biosynthesis, sorting, and function of cellular components within the cell. Concludes with examples of how cells perceive signals from other cells within cell populations, tissues, organisms, and the environment. Three hours of lab each week. Chemistry 225 is recommended.
240. Inorganic Chemistry
Jeffrey Nagle M  10:30 - 11:25
W  10:30 - 11:25
F  10:30 - 11:25
Druckenmiller-020
An introduction to the chemistry of the elements with a focus on chemical bonding, periodic properties, and coordination compounds. Topics in solid state, bioinorganic, and environmental inorganic chemistry also are included. Provides a foundation for further work in chemistry and biochemistry. Lectures and four hours of laboratory work per week.
252. Physical Chemistry II
Ronald Christensen T  10:00 - 11:25
TH 10:00 - 11:25
Druckenmiller-020
Development and principles of quantum mechanics with applications to atomic structure, chemical bonding, chemical reactivity, and molecular spectroscopy. Lectures and four hours of laboratory work per week. Mathematics 181 is recommended.. Note: Chemistry 251 is not a prerequisite for Chemistry 252.
263. Laboratory in Molecular Biology and Biochemistry
Peter Woodruff M  2:30 - 3:55Druckenmiller-004
Comprehensive laboratory course in molecular biology and biochemistry that reflects how research is conducted and communicated. Includes sequential weekly experiments, resulting in a cohesive, semester-long research project. Begins with genetic engineering to produce a recombinant protein, continues with its purification, and finishes with functional and structural characterization. Emphasis is on cloning strategy, controlling protein expression, and protein characterization using techniques such as polymerase chain reaction, affinity chromatography, isoelectric focusing, and high-performance liquid chromatography. Students also learn to manipulate data using structural and image analysis software.
310. Instrumental Analysis
Elizabeth Stemmler M  2:30 - 3:55
W  2:30 - 3:55
Druckenmiller-024
Theoretical and practical aspects of instrumental techniques, including nuclear magnetic resonance spectroscopy, infrared spectroscopy, Raman spectroscopy, and mass spectrometry are covered, in conjunction with advanced chromatographic methods. Applications of instrumental techniques to the analysis of biological and environmental samples are covered. Lectures and two hours of laboratory work per week.
331. Chemical Biology
Danielle Dube M  10:00 - 11:25
W  10:00 - 11:25
Druckenmiller-024
The power of organic synthesis has had a tremendous impact on our understanding of biological systems. Examines case studies in which synthetically derived small molecules have been used as tools to tease out answers to questions of biological significance. Topics include synthetic strategies that have been used to make derivatives of the major classes of biomolecules (nucleic acids, proteins, carbohydrates, and lipids), and the experimental breakthroughs these molecules have enabled (e.g., polymerase-chain reaction, DNA sequencing, microarray technology). Emphasis is on current literature, experimental design, and critical review of manuscripts.
350. Atmospheric Chemistry
Laura Voss T  2:30 - 3:55
TH 2:30 - 3:55
Druckenmiller-024
An in-depth study in the chemistry that affects atmospheric composition and global climate change. Topics include ozone depletion, tropospheric pollution, understanding past climates, and modern research techniques.