Location: Bowdoin / The College Catalogue / Courses / Chemistry / Courses

The College Catalogue

Chemistry – Courses

First-Year Seminars

For a full description of first-year seminars, see the First-Year Seminar section.

1011 {11} a. Great Issues in Science. Fall 2013. Daniel M. Steffenson.

Introductory, Intermediate, and Advanced Courses

1058 {58} a - INS. Drug Discovery. Fall 2013. Danielle Dube.

The process of drug discovery of medicinal compounds has evolved over millennia, from the shaman’s use of medicinal herbs to the highly evolved techniques of rational design and high-throughput screening used by today’s pharmaceutical industry. Examines past and present approaches to drug discovery, with an emphasis on the natural world as a source of drugs, historical examples of drug discovery, and the experiments undertaken to validate a drug. Encourages students to take initial steps to identify novel therapeutics and to directly compare conventional versus herbal remedies in integrated laboratory exercises. Assumes no background in science. Not open to students who have credit for a chemistry course numbered 1100 {100} or higher.

1059 {59} a - INS. Chemistry of Consumer Goods. Fall 2013. Yi Jin Gorske.

Natural and synthetic “chemicals” make up virtually everything we purchase and consume from breakfast cereals to soaps, shampoo bottles, and over-the-counter medications. Examines the chemical components of food, drugs, soaps, plastics, and other consumer goods we encounter daily. Explores scientific resources that can be used to obtain information on product components, safety, and regulations. Also considers topics related to some of the current safety concerns raised by chemicals found in common household items through case studies and research projects. Assumes no background in science. Not open to students who have credit for a chemistry course numbered 1100 {100} or higher.

1101 {101} a - INS. Introductory Chemistry I. Every fall. Michael P. Danahy and Jeffrey K. Nagle.

The first course in a two-semester introductory college chemistry sequence. Introduction to the states of matter and their properties, stoichiometry and the mole unit, properties of gases, thermochemistry, atomic structure, and periodic properties of the elements. Lectures, review sessions, and four hours of laboratory work per week. To ensure proper placement, students must take the chemistry placement examination and must be recommended for placement in Chemistry 1101 {101}. Students continuing in chemistry will take Chemistry 1102 {102}, not Chemistry 1109 {109}, as their next chemistry course.

1102 {102} a - MCSR, INS. Introductory Chemistry II. Every spring. The Department.

The second course in a two-semester introductory college chemistry sequence. Introduction to chemical bonding and intermolecular forces; characterization of chemical systems at equilibrium and spontaneous processes; the rates of chemical reactions; and special topics. Lectures, review sessions, and four hours of laboratory work per week. Students who have taken Chemistry 1109 {109} may not take Chemistry 1102 {102} for credit.

Prerequisite: Chemistry 1101 {101} or permission of the instructor.

1105 {105} a - MCSR, INS. Perspectives in Environmental Science. Every spring. Spring 2014. David R. Griffith and John Lichter.

Functioning of the earth system is defined by the complex and fascinating interaction of processes within and between four principal spheres: land, air, water, and life. Leverages key principles of environmental chemistry and ecology to unravel the intricate connectedness of natural phenomena and ecosystem function. Fundamental biological and chemical concepts are used to understand the science behind the environmental dilemmas facing societies as a consequence of human activities. Laboratory sessions consist of local field trips, laboratory experiments, group research, case study exercises, and discussions of current and classic scientific literature. (Same as Biology 1158 {158} and Environmental Studies 2201 {201}.)

Prerequisite: One course numbered 1100 {100} or higher in biology, chemistry, earth and oceanographic science, or physics.

1109 {109} a - MCSR, INS. General Chemistry. Every fall and spring. Fall 2013. Soren N. Eustis and David R. Griffith. Spring 2014. The Department.

A one-semester introductory chemistry course. Introduction to models of atomic structure, chemical bonding, and intermolecular forces; characterization of chemical systems at equilibrium and spontaneous processes; the rates of chemical reactions; and special topics. Lectures, review sessions, and four hours of laboratory work per week. Students who have taken Chemistry 1102 {102} may not take Chemistry 1109 {109} for credit. To ensure proper placement, students must take the chemistry placement examination and must be recommended for placement in Chemistry 1109 {109}.

2050 {205} a - INS. Environmental Chemistry. Spring 2014. David R. Griffith.

Focuses on two key processes that influence human and wildlife exposure to potentially harmful substances—chemical speciation and transformation. Equilibrium principles as applied to acid-base, complexation, precipitation, and dissolution reactions are used to explore organic and inorganic compound speciation in natural and polluted waters; quantitative approaches are emphasized. Weekly laboratory sections are concerned with the detection and quantification of organic and inorganic compounds in air, water, and soils/sediments. (Same as Earth and Oceanographic Science 2325 {206} and Environmental Studies 2255 {211}.)

Prerequisite: Chemistry 1109 {109}, placement in chemistry at the 2000 level, or a course numbered 2000–2969 {200–289} in chemistry.

2100 {210} a - MCSR, INS. Chemical Analysis. Every fall. Elizabeth Stemmler.

Methods of separating and quantifying inorganic and organic compounds using volumetric, spectrophotometric, electrometric, and chromatographic techniques are covered. Chemical equilibria and the statistical analysis of data are addressed. Lectures and four hours of laboratory work per week.

Prerequisite: Chemistry 1102 {102} or 1109 {109}, placement in chemistry at the 2000 level, or any course numbered 2000–2969 {200–289} in chemistry.

2250 {225} a. Organic Chemistry I. Every fall. Richard D. Broene, Michael P. Danahy, and Yi Jin Gorske.

Introduction to the chemistry of the compounds of carbon. Describes bonding, conformations, and stereochemistry of small organic molecules. Reactions of hydrocarbons, alkyl halides, and alcohols are discussed. Kinetic and thermodynamic data are used to formulate reaction mechanisms. Lectures, review sessions, and four hours of laboratory work per week.

Prerequisite: Chemistry 1102 {102} or 1109 {109}, placement in chemistry at the 2000 level, or any course numbered 2000–2969 {200–289} in chemistry.

2260 {226} a. Organic Chemistry II. Every spring. The Department.

Continuation of the study of the compounds of carbon. Highlights the reactions of aromatic, carbonyl-containing, and amine functional groups. Mechanistic reasoning provides a basis for understanding these reactions. Skills for designing logical synthetic approaches to complex organic molecules are developed. Chemistry 2250 {225} and 2260 {226} cover the material of the usual course in organic chemistry and form a foundation for further work in organic chemistry and biochemistry. Lectures, review sessions, and four hours of laboratory work per week.

Prerequisite: Chemistry 2250 {225}.

2310 {231} a. Fundamentals of Biochemistry. Fall 2014. Danielle H. Dube.

Focuses on the fundamentals of biochemistry. Topics include the influence of water on biomolecules; how structure dictates function; properties of the major classes of biomolecules (proteins, nucleic acids, carbohydrates, and lipids); enzyme mechanisms, kinetics, and regulation; metabolic transformations; energetics and metabolic control. Emphasis will be on how the physical and chemical properties of the universe impact living systems. This course does NOT satisfy a requirement for the biochemistry major and it is not open to students who have credit for Chemistry 2320 {232}. Students who intend to enroll in Chemistry 2320 {232} should not register for Chemistry 2310 {231}.

Prerequisite: Chemistry 2260 {226}.

2320 {232} a - MCSR. Biochemistry. Every spring. Danielle H. Dube.

Focuses on the chemistry of living organisms. Topics include structure, conformation, and properties of the major classes of biomolecules (proteins, nucleic acids, carbohydrates, and lipids); enzyme mechanisms, kinetics, and regulation; metabolic transformations; energetics and metabolic control. Lectures and four hours of laboratory work per week. This course satisfies a requirement for the biochemistry major; it is not open to students who have credit for Chemistry 2310 {231}.

Prerequisite: Chemistry 2260 {226}.

2400 {240} a - MCSR, INS. Inorganic Chemistry. Every spring. Jeffrey K. Nagle.

An introduction to the chemistry of the elements with a focus on chemical bonding, periodic properties, and coordination compounds. Topics in solid state, bioinorganic, and environmental inorganic chemistry also are included. Provides a foundation for further work in chemistry and biochemistry. Lectures and four hours of laboratory work per week.

Prerequisite: Chemistry 1102 {102} or 1109 {109}, or any course numbered 2000–2969 {200–289} in chemistry.

2510 {251} a - MCSR, INS. Chemical Thermodynamics and Kinetics. Every fall. Daniel M. Steffenson.

Thermodynamics and its application to chemical changes and equilibria that occur in the gaseous, solid, and liquid states. The behavior of systems at equilibrium and chemical kinetics are related to molecular properties by means of statistical mechanics and the laws of thermodynamics. Lectures and four hours of laboratory work per week. Mathematics 1800 {181} is recommended.

Prerequisite: Chemistry 1102 {102} or 1109 {109}, or any course numbered 2000–2969 {200–289} in chemistry; Mathematics 1700 {171} or higher; and Physics 1140 {104}; or permission of the instructor.

2520 {252} a - MCSR, INS. Quantum Chemistry and Spectroscopy. Every spring. Soren N. Eustis.

Development and principles of quantum chemistry with applications to atomic structure, chemical bonding, chemical reactivity, and molecular spectroscopy. Lectures and four hours of laboratory work per week. Mathematics 1800 {181} is recommended. Note: Chemistry 2510 {251} is not a prerequisite for Chemistry 2520 {252}.

Prerequisite: Chemistry 1102 {102} or 1109 {109}, or any course numbered 2000–2969 {200–289} in chemistry; Mathematics 1700 {171} or higher; and Physics 1140 {104}; or permission of the instructor.

2970–2973 {291–294} a. Intermediate Independent Study in Chemistry. The Department.

Laboratory or literature-based investigation of a topic in chemistry. Topics are determined by the student and a supervising faculty member. Designed for students who have not completed at least four of the courses numbered 2000–2969 {299–289} required for the chemistry major.

2999 {299} a. Intermediate Collaborative Study in Chemistry. The Department.

3040 {304} a. Advanced Environmental Chemistry. Fall 2013. David R. Griffith.

Every year, 300 million tons of synthetic organic chemicals enter natural waters. Examines the fate of organic contaminants in aquatic environments. Uses chemical structures and properties to predict contaminant partitioning, biodegradation, and transport, and to evaluate the implications for human health and aquatic ecosystems. Case studies on endocrine disrupting chemicals, oil spills, and pharmaceuticals allow critical examination of inherent tensions between compound-specific chemical analyses and toxicity bioassays, between studies of single-compounds and complex mixtures, and between empirical and predictive approaches. (Same as Environmental Studies 3903 {303}.)

Prerequisite: Chemistry 2250 {225}.

[3050 {305} a. Environmental Fate of Organic Chemicals. (Same as Environmental Studies 3905 {305}.)]

[3060 {306} a. Transformation of Organic Chemicals in the Environment. (Same as Environmental Studies 3906 {306}.)]

3100 {310} a. Instrumental Analysis. Spring 2014. Elizabeth A. Stemmler.

Theoretical and practical aspects of instrumental techniques, including nuclear magnetic resonance spectroscopy, infrared spectroscopy, Raman spectroscopy, and mass spectrometry are covered, in conjunction with advanced chromatographic methods. Applications of instrumental techniques to the analysis of biological and environmental samples are covered. Lectures and two hours of laboratory work per week.

Prerequisite: Chemistry 2100 {210} or permission of the instructor.

3200 {320} a. Advanced Organic Chemistry: Organometallic Chemistry. Fall 2013. Richard D. Broene.

In-depth study of compounds containing metal-carbon bonds and their reactions, with emphasis on synthesis and spectroscopy. A mechanistic approach is used to discover how these species act as catalysts or intermediates in synthetic organic reactions. Special techniques for handling these often sensitive molecules are introduced.

Prerequisite: Chemistry 2260 {226} and 2400 {240}.

[3250 {325} a. Structure Determination in Organic Chemistry.]

3270 {327} a. Biomimetic and Supramolecular Chemistry. Fall 2014 or Spring 2015. Benjamin C. Gorske.

A guided exploration of the primary scientific literature concerning weak covalent and noncovalent interactions that collectively determine the three-dimensional structures of biomimetic and foldameric molecules and that govern the aggregation of molecules into discrete multi-molecular assemblies. Surveys practical applications in biochemical investigation, catalysis, and medicine, as well as in the young but rapidly expanding sciences of molecular and nanostructural engineering.

Prerequisite: Chemistry 2260 {226}.

3310 {331} a. Chemical Biology. Spring 2014. Danielle H. Dube.

The power of organic synthesis has had a tremendous impact on our understanding of biological systems. Examines case studies in which synthetically derived small molecules have been used as tools to tease out answers to questions of biological significance. Topics include synthetic strategies that have been used to make derivatives of the major classes of biomolecules (nucleic acids, proteins, carbohydrates, and lipids) and the experimental breakthroughs these molecules have enabled (e.g., polymerase-chain reaction, DNA sequencing, microarray technology). Emphasis on current literature, experimental design, and critical review of manuscripts.

Prerequisite: Chemistry 2320 {232}.

[3400 {340} a. Advanced Inorganic Chemistry.]

4000–4003 {401–404} a. Advanced Independent Study in Chemistry. The Department.

Advanced version of Chemistry 2970–2973 {291–294}. Students are expected to demonstrate a higher level of ownership of their research problem and to have completed at least four of the intermediate courses (numbered 2000–2969 {200–289}) required for the major.

4029 {405} a. Advanced Collaborative Study in Chemistry. The Department.

4050–4051 a. Honors Project in Chemistry. The Department.

Online Catalogue content is current as of August 1, 2013. For most current course information, use the online course finder. Also see Addenda.