Barbarians at the gate: Adaptive evolution of squid-naive Vibrio fischeri to light organ symbiosis
- 3/6/2014 |
4:00 PM – 5:00 PM
Location: Druckenmiller Hall, Room 020
Event Type: Seminar
Cheryl Whistler, University of New Hampshire, Department of Molecular, Cellular & Biomedical Sciences
My current research focus will use the GacA mutant as a basis for identifying and characterization colonization traits. These studies will provide insight into bacteria-derived signals that allow hosts to respond appropriately to beneficial organisms, thus allowing association, without compromising the ability of immune responses to protect the host from pathogenic infection. We are currently utilizing a recently generated DNA microarray of the entire genome of V. fischeri, and will also combine this genomic approach with random mutagenesis screens to discover previously uncharacterized genes and traits that contribute to animal tissue colonization.